Watch Live Manchester United vs. Chelsea
The Red Devils have lost each of their two home games so far this term, with the most recent being the 6-1 hammering they received at the hands of Tottenham.
Bruno Fernandes and Marcus Rashford have been the difference-makers for Manchester United in the last couple of games and are certain starters in the attack. Cavani is likely to get the nod to lead the line against Chelsea, with Juan Mata, who has made a fine start to the season, could occupy the right-wing slot ahead of Greenwood.
Only once in their entire history have Man United lost each of their opening three home league games of a campaign, with that coming in 1930-31 as they went on to finish bottom of the table.
Manchester United Probable Lineup (4-2-3-1): de Gea, Wan-Bissaka, Tuanzebe, Maguire, Shaw, McTominay, Fred, Mata, Fernandes, Rashford, Cavani
Chelsea Probable Lineup (4-2-3-1): Mendy, James, Silva, Zouma, Chilwell, Kante, Kovacic, Pulisic, Havertz, Mount, Werner